Electric-trained stem cells will help beat the diseased heart

Electric-trained stem cells will help beat the diseased heart

Cardiac recovery

The use of stem cells to treat the consequences of severe cardiovascular diseases is one of the promising areas of modern cardiology. The main problem for today is the adaptation of implanted cells to the cardiac muscle in order to avoid their rejection.

One of the possible ways of cardiac rehabilitation is the creation of cardiomyocytes, cardiac muscle cells injected by injection. A team of researchers at Columbia University has developed a technique for adapting these cells before implantation using electrical stimulation.

The results of the work were told by professor of biomedical engineering Vonyak-Novakovich:

“We used electrical stimulation to” train “cells, regulate their contractile function and improve the ability to fuse with each other. By giving electrical impulses to the rhythm of the heartbeat, we “taught” the transplanted cell to participate in the work of the heart, to stimulate the formation of the necessary cardiac proteins, and helped it become more “adult”.

Currently, scientists are studying how the maturing heart develops its ability to palpitate, as well as the possibility of safe introduction of trained cardiomyocytes into the real heart muscle.

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